邮箱:jianzhang@henu.edu.cn; zhangjian861208@126.com
职称:副教授
研究方向:有机荧光染料的构建及应用研究
个人简介:
2006-2010 河北师范大学 学士
2010-2013 河南大学 硕士
2013-2017 复旦大学 博士
2017-至今 河南大学 副教授
发表论文:以第一作者(含共同一作)和通讯作者身份在Biosens. Bioelectron., Sensor. Actuat. B-Chem.,Chem. Eur. J., Nanomed-Nanotechnol.等杂志发表21篇,含ESI高被引论文1篇,封面论文2篇,期刊热点论文1篇。
主持项目:
1. 国家自然科学基金青年基金项目,21702046,靶向线粒体的BODIPY类近红外荧光探针的构建及在活性氮物种检测方面的应用,24.0万元,在研,主持。
2. 中国博士后科学基金面上资助,2018M632757,靶向线粒体的HNO近红外荧光探针的构建和应用,5.0万元,在研,主持。
代表性成果:
(1)Jian Zhang, Nannan Wang, Xin Ji, Yuanfang Tao, Jiamin Wang*, Weili Zhao*, Recent Progress in BODIPY-based Fluorescent Probes for Biothiols, Chem. Eur. J., 2019, DOI:10.1002chem.201904470.
(2) Jinhua Gao, Yuanfang Tao, Jian Zhang*, Nannan Wang, Xin Ji, Jinling He, Yubing Si, Weili Zhao*, Development of Lysosome-Targeted Fluorescent Probes for Cys by Regulating BODIPY Molecular Structure, Chem. Eur. J., 2019, 25:11246–11256.
(3)Jian Zhang, Xin Ji, Junliang Zhou, Zhongjian Chen, Xiaochun Dong, Weili Zhao*, Pyridinium Substituted BODIPY as NIR Fluorescent Probe for Simultaneous Sensing of Hydrogen Sulphide/glutathione and Cysteine/homocysteine, Sensor. Actuat. B-Chem., 2018, 257:1076–1082.
(4) Jian Zhang, Xin Ji, Hang Ren, Junliang Zhou, Zhongjian Chen, Xiaochun Dong, Weili Zhao*, Meso-heteroaryl BODIPY Dyes as Dual-responsive Fluorescent Probes for Discrimination of Cys from Hcy and GSH, Sensor. Actuat. B-Chem., 2018, 260: 861–869.
(5) Jian Zhang, Xiaolong Bao, Junliang Zhou, Fangfang Peng, Hang Ren, Xiaochun Dong, Weili Zhao*, A Mitochondria-targeted Turn-on Fluorescent Probe for the Detection of Glutathione in Living Cells, Biosens. Bioelectron., 2016, 85:164−170.